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OTC Medication for Dogs: 9 Effective Medicines for your Canine - 2021 Guide

Dogs are more than pets and emotional support animals and people consider them a part of their family. Dogs and cats make a great addition to your family and they offer a number of benefits also. Some of these benefits include constant companionship, unconditional love, emotional and mental support, and improvement in physical health, etc.

Besides pets, having emotional support animals is also something that now many of the Americans are moving towards getting their ESA. But before getting the ESA, you will have to get a valid ESA letter. An OTC or over-the-counter medication are the drugs that you can but without the vet’s prescription. 


However, like us, dogs could also contract diseases and allergies. These allergies could be due to many reasons and the reasons could either be seasonal or due to any specific reason. To treat and cure them, you will need to administer the right kind of drug or medication.

These medicines come in different forms including gels, creams, sprays, and tablets. To know about these OTC drugs that help in treating dog ailments, read on.


Antihistamines are used to treat allergies in dogs. Some of the famous and most commonly used antihistamines are Benadryl (diphenhydramine), Claritin (loratadine), and Zyrtec (cetirizine), and all of these are used to relieve the symptoms of the allergies. This kind of drug is usually safe or has minimal side effects with drowsiness being the most common symptom.

However, some antihistamines may contain ingredients like decongestants that could be harmful to your dog. The process of buying an antihistamine is somewhat similar to getting an emotional support animal letter since, in both of the processes, you need to be careful of what you are getting.


This drug is used to manage motion sickness and pet and ESA owners use it to keep their dogs calm during traveling. Though the medicine is generally considered safe for dogs but for maximum benefits, you must use the one that is specifically formulated and made for dogs. As an emotional support dog letter helps you live with your ESA, a canine-specific Dramamine will help you travel peacefully.

Hydrogen Peroxide

Hydrogen peroxide is a go-to drug for any dog owner and is an absolute must weapon in a dog owner’s arsenal or first aid kit. The medicine is used to clean and treat topical wounds and broken skin and in some cases, it is also helpful in instigating vomits if your dog has ingested something that is harmful to him.

However, instead of giving any drug yourself, it is better to contact your vet if any such thing happens.


This drug is used to treat vomiting and diarrhea in dogs. The dosage for Pepto-Bismol is 1 teaspoon for a 5 to 10 pounds dog but if your dog does not respond well to the medication then call your vet immediately.


Like Pepto-Bismol, Imodium is also used to treat diarrhea in dogs. It is a safe medication and as per the dosage, you will need to give 1 mg per 20 pounds of bodyweight. Unlike other medicines that you will have to give a few doses of, you will have to give just one dose. 

If diarrhea does not get better then do not give another dose but call your veterinarian. Some diseases need specific medicine and the vet will guide you better.

Buffered Aspirin, Tylenol and Ibuprofen

Buffered aspirin is considered somewhat safe for dogs but still, its coated tablets may not be that good and cause digestive issues in your dog. As far as Tylenol and Ibuprofen are concerned, they are not safe for your dog and you should not administer it to your canine.

In the case of aspirin, it may cause some side effects like an increased risk of bleeding and some other health issues. If your dog shows signs of arthritis, fever, and ache then it is better to get the right medicine for your dog.


This is also a good drug that helps in treating and relieving diarrhea in dogs. However, besides diarrhea, it also helps in soothing your dog’s upset stomach. But since you will have to administer 1 ml per pound of body weight, if you have a large dog, you will have to give a lot of it to your dog.

Cough Medication

There are a number of OTC medications for your dog that help in treating the symptoms and the ingredients are safe for your dog. However, instead of administering the drug every time your dog contracts cough, it is better to get him checked for a more serious illness like heartworms, respiratory issues, and cardiac issues. 

An emotional support dog letter helps you in keeping your ESA canine but you will have to be watchful of your dog and make sure that he is healthy.

Pepcid AC (famotidine) and Tagamet (cimetidine)

This drug works for both the dogs and the dog owners. They work in a dog’s system in the same way as they work for a human body system. It decreases the production of gastro-intestinal acids and makes your canine feel better. The problem in the digestive system could be due to any reasons and if the condition stays for long then it is better to consult the vet.

All of these over-the-counter drugs work safely and effectively for your dog and besides a valid ESA letter online, you will have to know about a safe and effective drug for your dog. This will help you keep your canine healthy and avoid any serious issues.